HPLC - UV/VIS Spectroscopy
Fibre Optic and Diode Array Applications
Software - Fluorescence
| Overview | Specifications | Ordering Information | Print Version | Documentation |
Geminyx Chromatography Data Systems are the latest in a long line of Data System packages dating back over the last 25 years.System Control
Geminyx has comprehensive control capabilities for many HPLC modules including the Knauer range of HPLC systems and modules shown here as well as for all Kontron and Bio-Tek Instruments HPLC hardware.
Precise Data Collection
A high resolution, self-calibrating, fast analogue-to-digital converter with a wide dynamic range, automatic sampling rate optimisation for data point storage and parameter free integration for increased productivity will ensure that you always obtain the correct data from your analysis.
System Suitability Test
Included in all Geminyx data system packages is a System Suitability Test with control chart graphics, comprehensive diode array spectral handling support and export to Microsoft Excel for automated, user defined calculations.
Professional Result Reporting
Geminyx has its own powerful reporting tools, which do not require additional application software. A dynamic link to Microsoft Word is also supported for more customised report publishing and external presentations.
21CFR Part 11 Compliance
A fully 21CFR Part 11 compliant version, including user management, audit trail, complete data and document history management with electronic signatures, is now available with upgrade options for all current Geminyx and KromaSystem 2000 users.
The latest versions of Geminyx are available in two standard packages: a standard version and a 21CFR Part 11 compliant version, which requires use of an Oracle or SQL Data Base.
Special Upgrade Offers
Upgrade packages are also available for users of earlier versions of Kontron Instruments D450 and MT2 software plus the KromaSystem 2000 NT version. These upgrades will allow you to migrate to newer computer environments, e.g. PCI PC architectures and also newer operating system software, or to become 21CFR Part 11 compliant without the need to consider changing your HPLC hardware.
Geminyx runs under Windows NT4.0, Windows 2000 and Windows XP.
| Sample Management | ||||
| File structure | Each sample sequence is embedded in a file, which contains all references for the analysis including control programs, integration methods, calibration information and reporting requirements. | |||
| Sharing | Control programs, integration methods, calibration information and reporting requirements can be shared and are thus usable with any number of sample sequences. | |||
| Data protection | Sample sequences are protected from accidental overwriting. | |||
| Batch sequencing | Sample sequences can be linked together to run consecutively. | |||
| Automatic shutdown | User-definable shutdown programs can be automatically started in a batch. | |||
| Online interaction | Any manual interactions during processing of a sequence requires confirmation and is recorded. | |||
| Control and Data Acquisition | ||||
| Instrument control | Control of one or two complete chromatography systems, full support for all Kontron Instruments and Biotek Instruments HPLC modules, control of other equipment via RS232 or relays. | |||
| Data acquisition | Direct digital acquisition from diode array detector, analogue acquisition via A/D control card. | |||
| Number of channels | Collection of data from maximum of 9 channels (6 analogue and/or 8 DAD chromatogram channels plus spectra). | |||
| Free channels | Analogue channels may be defined as free channels to be started on independent time bases. | |||
| A/D Control card | Six independent channels, 24 bit A/D conversion providing 1 µV resolution over the complete range from -1 V to +9 V, auto-calibration of A/D converter at the start of each run for maximum accuracy and reliability, each channel has its own synchronisation input for start of acquisition etc. Six potential-free programmable relay outputs for control of external devices, e.g fraction collection. | |||
| Programmable triggers | On-line peak detection for triggering control of fraction collectors or column switching in real time, control cn be based on level, threshold and time window. | |||
| Integration | ||||
| Parameters | Integration parameters for peak detection are automatically optimised for each peak individually. | |||
| Reprocessing | Chromatograms can be re-processed in either batch mode or singly, manual manipulation of baselines and peak markers with re-integration possible. | |||
| Parameter control | Automatic control of parameters, e.g. Integrate inhibit, possible using a time-controlled parameter table embedded in the defined analysis conditions. | |||
| Component identification | Using peak table with defined retention time conditions and windows for each component, with diode arary detection spectral matching is also possible. | |||
| Grouping | Grouping of peaks in the peak table is supported. | |||
| Chromatogram manipulation | Overlay, Zooming, Subtraction and Addition of chromatograms with factor definitions is supported. A chromatogram can be automatically subtracted during online batch acquisition. | |||
| Spectral Handling | ||||
| Online display | Contour or 3-dimensional plot with freely selectable viewing angle and viewing distance, peak purity. | |||
| Extraction | Mouse-controlled extraction of both spectra and chromatograms | |||
| Spectra library | Creation of new spectra libraries is supported, search for component identification in different libraries possible. | |||
| Peak purity | Online peak purity calculation with graphical display and spectra report | |||
| Spectra index | Automatic extraction to store all significant information | |||
| Lambda maximum | Lambda maximum function searches for optimum integration path | |||
| Quantification | ||||
| Calculation | Based on either area or height | |||
| Method | Internal, internal weighted and external standard are supported. | |||
| Calibration | Linear or quadratic with or without offset, exponential. | |||
| Multiple calibration | Using diluted or individually balanced standards, including bracketing. | |||
| System Suitablity Testing | ||||
| System check | Automatic checking of selectable values, e.g. retention time, relative retention time, calibration etc. | |||
| Statistics | Statistical evaluation of sample or standard sequences for a rapid overview of sequence quality. | |||
| Control Charts | Graphical evaluation of values in a sequence, e.g. retention time | |||
| Reporting | ||||
| Standard report | User-definable standard print-out | |||
| Report manager | User-configurable report manager for designing custom reports via Microsoft Word, direct link to Word and export in batch mode | |||
| Export | Direct export to Microsoft Excel is supported in batch mode, direct execution of macro-programs supported | |||
| 21CFR Part 11 Compliance | ||||
| Architecture | Client/Server architecture using one configuration for all connected clients | |||
| User identification | System start is only possible with valid user log-in and password | |||
| Password | Minimum length, maximum validity and minimum difference definable | |||
| Access rights | Definition for each individual application function and user group | |||
| Audit trail | Time of action, User name, PC workstation location, Importance level, Description of the action. | |||
| Revision management | Comprehensive Document Management System for absolute traceability | |||
| Electronic signature | For the levels Author, Quality Management, Review and Final, data sets can be locked after signing | |||
| Database | Support for Microsoft SQL 7 or 2000 and Oracle versions 7, 8 and 9 | |||
| All specifications may be subject to change for technical reasons. | ||||
| GEM-00001 | Geminyx HPLC Software, Reprocessing version |
| GEM-00002 | Geminyx HPLC Software for operation with diode array detector |
| GEM-00003 | Geminyx HPLC Software for 1 System including A/D Control card |
| GEM-00004 | Geminyx HPLC Software for 2 Systems including A/D Control card |
| GEM-00005 | Geminyx HPLC Software, Integration Pack including A/D Control card |
| GEM-DB001 | Geminyx 21CFR Part 11 compliant HPLC Software, Reprocessing version |
| GEM-DB002 | Geminyx 21CFR Part 11 compliant HPLC Software for operation with diode array detector |
| GEM-DB003 | Geminyx 21CFR Part 11 compliant HPLC Software for 1 System including A/D Control card |
| GEM-DB004 | Geminyx 21CFR Part 11 compliant HPLC Software for 2 Systems including A/D Control card |